In recent years, colorectal cancer (CRC) has emerged as the third most common malignancy globally,the second leading cause of cancer-related mortality, underscoring the urgent need for novel therapeutic strategies. Immune checkpoint blockade (ICB) therapy has been proven to provi...

The research team led by Professor Guodong Chen from the First Affiliated Hospital of University of South China has published a cutting-edge paper titled “Conversion Therapy Strategy: A Novel GPC3-Targeted Multimodal Organic Phototheranostics Platform for Mid-late-stage Hepatocel...

Currently, metabolic disordershave become a major global public health challenge, posing a serious threat to socioeconomic development. In China, the number of adults withdiabetes exceeds141 million, the highestin the world; meanwhile, the prevalence of metabolic-associatedfatty...

Atypical teratoid rhabdoid tumor (ATRT) is a rare but highly aggressive pediatric tumoraffectingthe brainspinal cord. The hallmark of this disease is the loss of the SMARCB1 gene, a key driver mutation that causessignificantupregulationofEZH2, a proteincritical fortumor growth. A...

In recent years, the global reported incidence of thyroid cancer has been continuously increasing. Although most papillary thyroid carcinomas present an indolent clinical course, there are still some cases that developlocaldistant metastases. In cases of recurrencemetastasis, whi...